krit.club logo

Transport in Animals - Blood and lymphatic vessels

Grade 12IGCSEBiology

Review the key concepts, formulae, and examples before starting your quiz.

🔑Concepts

Arteries have thick walls with a high proportion of elasticelastic fibersfibers and smoothsmooth musclemuscle to withstand and maintain high blood pressure from the heart.

Capillaries are the site of exchange; their walls are composed of a single layer of endothelialendothelial cells, providing a short diffusion path for O2O_2, CO2CO_2, and C6H12O6C_6H_{12}O_6.

Veins contain valvesvalves to ensure the one-way flow of blood back to the heart against gravity under low pressure.

The mammalian circulatory system is a doubledouble circulatorycirculatory systemsystem: the pulmonary circulation (lungs) and the systemic circulation (body).

Tissue fluid is formed when high hydrostatichydrostatic pressurepressure at the arterial end of capillaries forces water and small solutes out of the plasmaplasma.

The lymphatic system collects excess tissue fluid, now called lymphlymph, and returns it to the circulatory system via the subclaviansubclavian veinsveins.

Red blood cells contain haemoglobinhaemoglobin (HbHb), which binds reversibly with oxygen to form oxyhaemoglobinoxyhaemoglobin (HbO8HbO_8 or Hb(O2)4Hb(O_2)_4).

📐Formulae

Cardiac Output=Heart Rate×Stroke VolumeCardiac\ Output = Heart\ Rate \times Stroke\ Volume

Hb+4O2Hb(O2)4Hb + 4O_2 \rightleftharpoons Hb(O_2)_4

CO2+H2Ocarbonic anhydraseH2CO3H++HCO3CO_2 + H_2O \xrightleftharpoons{carbonic\ anhydrase} H_2CO_3 \rightleftharpoons H^+ + HCO_3^-

Pnet=(PcapillaryPinterstitial)(πcapillaryπinterstitial)P_{net} = (P_{capillary} - P_{interstitial}) - (\pi_{capillary} - \pi_{interstitial})

💡Examples

Problem 1:

Calculate the cardiac output of a student whose heart rate is 7272 beats per minute and whose stroke volume is 7070 cm3cm^3. State the result in dm3 min1dm^3\ min^{-1}.

Solution:

72 bpm×70 cm3=5040 cm3 min172 \text{ bpm} \times 70\ cm^3 = 5040\ cm^3\ min^{-1} 5040÷1000=5.04 dm3 min15040 \div 1000 = 5.04\ dm^3\ min^{-1}

Explanation:

Cardiac output is the total volume of blood pumped by the left ventricle per minute. It is calculated by multiplying the Heart RateHeart\ Rate by the Stroke VolumeStroke\ Volume and converting units from cm3cm^3 to dm3dm^3 by dividing by 10001000.

Problem 2:

Describe the change in the affinity of HbHb for O2O_2 when the partial pressure of CO2CO_2 (pCO2pCO_2) increases.

Solution:

An increase in pCO2pCO_2 leads to the Bohr shiftBohr\ shift. The oxygen dissociation curve shifts to the right, meaning HbHb has a lower affinity for O2O_2 and releases it more readily to respiring tissues.

Explanation:

Increased CO2CO_2 reacts with H2OH_2O to form H+H^+, lowering the pHpH. This change in acidity alters the tertiary structure of haemoglobinhaemoglobin, facilitating the unloading of O2O_2 where it is needed most.

Blood and lymphatic vessels - Revision Notes & Key Diagrams | IGCSE Grade 12 Biology