Review the key concepts, formulae, and examples before starting your quiz.
🔑Concepts
Chromosomes are thread-like structures made of DNA and proteins, found in the nucleus. They carry genetic information in the form of genes. In humans, the diploid number is and the haploid number is .
A gene is defined as a length of DNA that codes for a specific protein. Alleles are alternative forms of a gene that occupy the same locus on a chromosome.
DNA is a double helix consisting of two strands of nucleotides. Each nucleotide contains a phosphate group, a deoxyribose sugar, and a nitrogenous base: Adenine (), Thymine (), Cytosine (), or Guanine ().
DNA controls cell function by controlling the production of proteins (enzymes, antibodies, and receptors). The sequence of bases in a gene determines the sequence of amino acids used to build a specific protein.
Protein synthesis involves two stages: Transcription, where an molecule is made from the DNA template in the nucleus, and Translation, where the ribosome reads the codons to assemble amino acids into a polypeptide chain.
The genetic code is a triplet code. Each sequence of three bases, called a codon (e.g., , ), specifies one amino acid.
📐Formulae
💡Examples
Problem 1:
A specific protein consists of amino acids. Calculate the minimum number of nitrogenous bases in the gene that codes for this protein.
Solution:
Explanation:
Since each amino acid is coded for by a triplet of bases (a codon), you multiply the number of amino acids by to find the number of bases.
Problem 2:
If a double-stranded DNA molecule contains Cytosine (), calculate the percentage of Thymine () in the molecule.
Solution:
- If , then .
- .
- .
- .
Explanation:
According to complementary base pairing rules, the amount of Cytosine equals Guanine, and the amount of Adenine equals Thymine.
Problem 3:
Identify the sequence transcribed from the DNA template strand sequence: .
Solution:
Explanation:
During transcription, pairs with (Uracil in ), pairs with , pairs with , and pairs with . The strands are antiparallel.