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Molecular Basis of Inheritance

Each subtopic includes About section, revision page link, 10 preview questions, and practice CTAs.

Structure of DNA and RNA

Subtopic

Structure of DNA and RNA under Molecular Basis of Inheritance for Grade 12 CBSE.

About Topic & Revision

Preview questions (no answers)

  1. 1.

    The length of DNA is usually defined as the number of:

    A.

    Nucleosides

    B.

    Phosphate groups

    C.

    Base pairs

    D.

    Sugar molecules

  2. 2.

    The discovery of the double helix was a milestone in biology. Who were the scientists awarded the Nobel Prize for this discovery along with Maurice Wilkins?

    A.

    Griffith and Avery

    B.

    Watson and Crick

    C.

    Hershey and Chase

    D.

    Meselson and Stahl

  3. 3.

    Which of the following is a pyrimidine found in DNA but not in RNA?

    A.

    Cytosine

    B.

    Adenine

    C.

    Thymine

    D.

    Uracil

Download the worksheet for Molecular Basis of Inheritance - Structure of DNA and RNA to practice offline. It includes additional chapter-level practice questions.

DNA Packaging

Subtopic

DNA Packaging under Molecular Basis of Inheritance for Grade 12 CBSE.

About Topic & Revision

Preview questions (no answers)

  1. 1.

    A typical nucleosome along with H1 histone is sometimes referred to as a:

    A.

    Nucleoid

    B.

    Chromatosome

    C.

    Centromere

    D.

    Kinetochore

  2. 2.

    Which of these is the first level of DNA packaging in eukaryotes?

    A.

    Solenoid

    B.

    Nucleosome

    C.

    Chromatid

    D.

    Chromosome

  3. 3.

    Which molecule acts as the 'string' in the beads-on-a-string structure of chromatin?

    A.

    Histone

    B.

    DNA

    C.

    RNA

    D.

    NHC protein

Download the worksheet for Molecular Basis of Inheritance - DNA Packaging to practice offline. It includes additional chapter-level practice questions.

DNA Replication

Subtopic

DNA Replication under Molecular Basis of Inheritance for Grade 12 CBSE.

About Topic & Revision

Preview questions (no answers)

  1. 1.

    The replication of DNA is an energetically expensive process. The energy is derived by the hydrolysis of:

    A.

    ATP only

    B.

    Pyrophosphate from dNTPs

    C.

    GTP only

    D.

    Glucose

  2. 2.

    Why does DNA replication require an RNA primer?

    A.

    To provide a template

    B.

    To provide a free 33'-OH group for DNA polymerase

    C.

    To unwind the DNA

    D.

    To provide energy

  3. 3.

    How many origins of replication are generally present in the circular DNA of E.coliE. coli?

    A.

    One

    B.

    Hundreds

    C.

    Thousands

    D.

    None

Download the worksheet for Molecular Basis of Inheritance - DNA Replication to practice offline. It includes additional chapter-level practice questions.

Transcription

Subtopic

Transcription under Molecular Basis of Inheritance for Grade 12 CBSE.

About Topic & Revision

Preview questions (no answers)

  1. 1.

    What is the result of the transcription process?

    A.

    A polypeptide chain

    B.

    A new DNA strand

    C.

    An RNA molecule

    D.

    A ribosome

  2. 2.

    The information for protein synthesis is carried by:

    A.

    rRNA

    B.

    tRNA

    C.

    mRNA

    D.

    snRNA

  3. 3.

    Which part of the eukaryotic RNA is removed during processing?

    A.

    Exons

    B.

    Introns

    C.

    5' Cap

    D.

    Poly-A tail

Download the worksheet for Molecular Basis of Inheritance - Transcription to practice offline. It includes additional chapter-level practice questions.

Genetic Code

Subtopic

Genetic Code under Molecular Basis of Inheritance for Grade 12 CBSE.

About Topic & Revision

Preview questions (no answers)

  1. 1.

    If the genetic code were hypothesized to be a 'quadruplet' code (consisting of a sequence of four nitrogenous bases per codon) instead of the standard triplet code, how many total possible codons could be generated using the four standard nitrogenous bases?

    A.

    16

    B.

    64

    C.

    128

    D.

    256

  2. 2.

    Which scientist(s) shared the Nobel Prize in 1968 for their work on the interpretation of the genetic code and its function in protein synthesis?

    A.

    Nirenberg, Khorana, and Holley

    B.

    Watson and Crick

    C.

    Hershey and Chase

    D.

    Meselson and Stahl

  3. 3.

    The term 'nonsense codon' is another name for:

    A.

    Start codon

    B.

    Stop codon

    C.

    Anticodon

    D.

    Degenerate codon

Download the worksheet for Molecular Basis of Inheritance - Genetic Code to practice offline. It includes additional chapter-level practice questions.

Translation

Subtopic

Translation under Molecular Basis of Inheritance for Grade 12 CBSE.

About Topic & Revision

Preview questions (no answers)

  1. 1.

    Translation occurs in which part of a eukaryotic cell?

    A.

    Nucleus

    B.

    Cytoplasm

    C.

    Nucleolus

    D.

    Lysosome

  2. 2.

    The 'Opal' stop codon is another name for:

    A.

    UAAUAA

    B.

    UAGUAG

    C.

    UGAUGA

    D.

    GUAGUA

  3. 3.

    Which site on the ribosome is responsible for holding the tRNA that is carrying the next amino acid to be added?

    A.

    P site

    B.

    A site

    C.

    E site

    D.

    T site

Download the worksheet for Molecular Basis of Inheritance - Translation to practice offline. It includes additional chapter-level practice questions.

Regulation of Gene Expression

Subtopic

Regulation of Gene Expression under Molecular Basis of Inheritance for Grade 12 CBSE.

About Topic & Revision

Preview questions (no answers)

  1. 1.

    The control of gene expression ensures that genes are expressed:

    A.

    At all times in all cells

    B.

    Only when their products are needed

    C.

    Randomly during the life cycle

    D.

    Only during cell death

  2. 2.

    Which enzyme from the laclac operon is responsible for the transacetylation of β\beta-galactosides?

    A.

    Transacetylase

    B.

    Permease

    C.

    Hydrolase

    D.

    Isomerase

  3. 3.

    When lactose enters the cell, it acts as an inducer and binds to the:

    A.

    Operator

    B.

    Promoter

    C.

    Repressor

    D.

    Structural gene zz

Download the worksheet for Molecular Basis of Inheritance - Regulation of Gene Expression to practice offline. It includes additional chapter-level practice questions.

Human Genome Project (HGP)

Subtopic

Human Genome Project (HGP) under Molecular Basis of Inheritance for Grade 12 CBSE.

About Topic & Revision

Preview questions (no answers)

  1. 1.

    Which of the following describes the percentage of the genome that consists of repeated sequences?

    A.

    Very small portion

    B.

    Exactly 10%10\%

    C.

    A large portion

    D.

    No portion at all

  2. 2.

    Which of these organisms was sequenced to help understand its role in research as a fruit fly model?

    A.

    Caenorhabditis elegans

    B.

    Arabidopsis

    C.

    Drosophila melanogaster

    D.

    Oryza sativa

  3. 3.

    The 'L' in the ELSI program associated with HGP stands for which of the following?

    A.

    Linear

    B.

    Life

    C.

    Legal

    D.

    Linkage

Download the worksheet for Molecular Basis of Inheritance - Human Genome Project (HGP) to practice offline. It includes additional chapter-level practice questions.

DNA Fingerprinting

Subtopic

DNA Fingerprinting under Molecular Basis of Inheritance for Grade 12 CBSE.

About Topic & Revision

Preview questions (no answers)

  1. 1.

    In the technique of DNADNA fingerprinting, when comparing the VNTRVNTR profiles of a child and their biological parents, which of the following observations is expected?

    A.

    The child's DNADNA bands are completely unique and do not correspond to either parent.

    B.

    The child's DNADNA bands match the maternal grandmother's profile only.

    C.

    Every VNTRVNTR band in the child's profile must be present in either the mother's or the father's profile.

    D.

    The child's DNADNA bands match the father's profile exactly, showing no maternal contribution.

  2. 2.

    The pattern of bands obtained in DNADNA fingerprinting is:

    A.

    Identical for all humans

    B.

    Unique to an individual (except identical twins)

    C.

    Always changing with age

    D.

    Different in blood and hair of the same person

  3. 3.

    Why does DNADNA fingerprinting use non-coding repetitive sequences?

    A.

    Because they are the same in everyone

    B.

    Because they show high variability between individuals

    C.

    Because they are easy to convert to proteins

    D.

    Because they are only found in plants

Download the worksheet for Molecular Basis of Inheritance - DNA Fingerprinting to practice offline. It includes additional chapter-level practice questions.