Diseases and Immunity
Each subtopic includes About section, revision page link, 10 preview questions, and practice CTAs.
Pathogens and transmission
SubtopicPathogens and transmission under Diseases and Immunity for Grade 11 IGCSE.
Preview questions (no answers)
- 1.
What is the name for the protein molecule on a pathogen's surface that triggers an immune response?
A.Antibody
B.Antigen
C.Antibiotic
D.Antiseptic
- 2.
Which of the following is a symptom of many food-borne infections like cholera?
A.Stronger bones
B.Improved vision
C.Severe diarrhea
D.High levels of red blood cells
- 3.
What is the importance of having a clean water supply for a community?
A.It makes the water look clearer for swimming
B.It prevents the transmission of water-borne pathogens
C.It ensures that people can wash their cars more easily
D.It prevents people from getting genetic diseases
- 4.
How does wearing a mosquito net at night help prevent malaria?
A.It kills the protoctist in the air
B.It acts as a mechanical barrier preventing mosquitoes from biting humans
C.It filters the air to remove viral particles
D.It keeps the person warm so their immune system works better
- 5.
Which of the following would be the most effective way to prevent the spread of a disease known to be transmitted by aerosol droplets?
A.Encouraging people to use insect repellent
B.Improving the ventilation in public buildings and schools
C.Installing more water filtration systems in the city
D.Increasing the frequency of street cleaning
- 6.
Why is the disposal of household waste in covered bins considered a hygienic practice?
A.It prevents the waste from getting wet and smelling bad
B.It prevents flies and rodents from accessing the waste and spreading pathogens
C.It encourages the waste to decompose faster through anaerobic respiration
D.It prevents the sun from bleaching the color of the waste
- 7.
Which of the following describes the 'indirect' transmission of a disease?
A.Pathogens passing from a mother to her baby during breastfeeding
B.Pathogens transferring from a person to a surface, and then to another person
C.Pathogens moving from one person to another through a handshake
D.Pathogens being injected into the blood during a blood transfusion
- 8.
Which statement best describes why 'hand-washing with soap' is more effective at preventing the transmission of enveloped viruses (like SARS-CoV-2) than just using water alone?
A.Soap molecules are small enough to enter the virus and stop its metabolism.
B.Soap molecules have a hydrophobic tail that inserts into the viral lipid envelope and disrupts its integrity.
C.Soap changes the pH of the water to 14, which melts the viral proteins.
D.Soap acts as a catalyst that speeds up the natural decay of the viral RNA.
- 9.
In the lifecycle of a flea-borne pathogen like Yersinia pestis (plague), the bacteria form a biofilm in the flea's digestive tract, blocking it. How does this 'blockage' specifically increase the transmission to a human host?
A.It causes the flea to starve, making it bite more hosts and regurgitate the bacteria into the bite wound.
B.It makes the flea fly faster, allowing it to cover more distance between hosts.
C.It prevents the flea from reproducing, so all its energy goes into biting.
D.It makes the flea's saliva more acidic, which dissolves human skin.
- 10.
Why is it biologically difficult to develop a single vaccine that prevents the transmission of all types of 'Common Cold' viruses?
A.The cold is caused by hundreds of different viruses, including Rhinoviruses and Coronaviruses, which have different surface antigens.
B.Common cold viruses do not have any antigens on their surface for the immune system to recognize.
C.The viruses only infect dead cells, which the immune system cannot target.
D.Vaccines can only be made for bacterial diseases, not viral ones.
Download the worksheet for Diseases and Immunity - Pathogens and transmission to practice offline. It includes additional chapter-level practice questions.
Body defences
SubtopicBody defences under Diseases and Immunity for Grade 11 IGCSE.
Preview questions (no answers)
- 1.
Which of the following is true about antigens?
A.They are always beneficial to the body
B.They are found on the surface of cells and viruses
C.They are produced by the brain to fight infection
D.They are a type of white blood cell
- 2.
Which of the following cells are primarily involved in the 'secondary' immune response?
A.Red blood cells
B.Memory cells
C.Platelets
D.Stem cells
- 3.
When a phagocyte digests a pathogen, what does it use to break the pathogen down?
A.Sunlight
B.Enzymes
C.Hormones
D.Carbon dioxide
- 4.
Which part of a lymphocyte actually produces the antibody proteins?
A.The cell wall
B.The ribosomes
C.The flagellum
D.The chloroplasts
- 5.
Which sequence correctly represents the 'lines of defense' a pathogen faces when trying to infect a human via the respiratory system?
A.Mucus -> Lymphocytes -> Phagocytes
B.Antibodies -> Skin -> Stomach Acid
C.Nose hairs -> Mucus -> Phagocytes
D.Stomach Acid -> Cilia -> Mucus
- 6.
What is the role of 'antigen-antibody complexes' in the immune response?
A.They are used to build new cell walls for the body's cells.
B.They make pathogens more visible and accessible to phagocytes.
C.They provide the energy needed for lymphocytes to divide.
D.They act as a chemical signal to stop the production of red blood cells.
- 7.
How does the body typically respond to a pathogen that has bypassed the skin through a cut?
A.By decreasing the flow of blood to the area to starve the bacteria.
B.By increasing the production of mucus in the lungs.
C.By sending phagocytes to the area to engulf and destroy the invaders.
D.By releasing stomach acid into the bloodstream to kill the bacteria.
- 8.
Which statement accurately compares active and passive immunity?
A.Active immunity is immediate, while passive immunity takes weeks to develop.
B.Active immunity involves the production of memory cells, whereas passive immunity does not.
C.Passive immunity results from a vaccine, while active immunity results from an infection.
D.Active immunity lasts for a short time, while passive immunity is permanent.
- 9.
In an autoimmune disease like Type 1 Diabetes, what is the 'antigen' that the immune system mistakenly targets?
A.A virus that has entered the pancreas.
B.A toxin produced by bacteria in the gut.
C.Proteins found on the surface of the body's own insulin-producing cells.
D.The glucose molecules circulating in the bloodstream.
- 10.
Which of the following best describes the 'chemical barrier' in the eyes?
A.The eyelashes, which trap dust and larger particles.
B.The rapid blinking reflex that physically removes pathogens.
C.Tears, which contain lysozyme enzymes that break down bacterial cell walls.
D.The thick layer of mucus that prevents pathogens from touching the cornea.
Download the worksheet for Diseases and Immunity - Body defences to practice offline. It includes additional chapter-level practice questions.
Antibodies and vaccination
SubtopicAntibodies and vaccination under Diseases and Immunity for Grade 11 IGCSE.
Preview questions (no answers)
- 1.
Which of these is the first line of defense before the antibody response starts?
A.Memory cells
B.The skin and mucous membranes
C.Plasma cells
D.Specific antibodies
- 2.
Which of the following would result in the shortest duration of immunity?
A.Catching the flu
B.Getting a chickenpox vaccine
C.Receiving an injection of ready-made antibodies
D.Recovering from a bacterial infection
- 3.
When a person receives a 'booster' shot, what is the intended effect?
A.To remove the old antibodies
B.To increase the number of memory cells and antibody levels
C.To introduce a new type of disease
D.To decrease the immune response
- 4.
Which of these is a benefit of being vaccinated?
A.It makes the person immune to all diseases for life
B.It prevents the person from ever needing to eat
C.It reduces the risk of getting seriously ill from a specific pathogen
D.It changes the person's DNA
- 5.
In the immune response, what is the specific role of the 'plasma cells' (a type of lymphocyte)?
A.They transform into phagocytes when an infection occurs
B.They secrete large quantities of antibodies into the blood
C.They store information about the pathogen for decades
D.They carry oxygen to the site of an infection
- 6.
What is the function of the cilia found in the lining of the respiratory tract?
A.To produce mucus to trap pathogens
B.To sweep mucus containing trapped pathogens away from the lungs
C.To produce antibodies to kill bacteria in the air
D.To increase the surface area for oxygen absorption
- 7.
Why is it difficult to develop a single vaccine for the common cold?
A.The viruses that cause it do not have antigens
B.The viruses mutate frequently, changing their surface antigens
C.The body cannot produce antibodies against cold viruses
D.Cold viruses only infect the mechanical barriers of the body
- 8.
Why does a vaccine contain a weakened or dead form of a pathogen?
A.To ensure the pathogen can still kill some cells to trigger a response.
B.To provide the antigens necessary to stimulate an immune response without causing disease.
C.To allow the pathogen to hide in the body for long-term protection.
D.To make it easier for the antibodies to kill the pathogen.
- 9.
How does the immune system 'remember' a pathogen?
A.By storing a copy of the pathogen's DNA in the brain.
B.By maintaining a population of long-lived memory B-cells.
C.By keeping a high concentration of antibodies in the blood forever.
D.By changing the shape of all white blood cells to match the pathogen.
- 10.
Which of the following describes 'active' immunity?
A.Acquiring antibodies from an external source.
B.The defense against a pathogen by the production of antibodies in the body.
C.The use of antibiotics to kill bacteria in the gut.
D.The physical movement of white blood cells toward an infection.
Download the worksheet for Diseases and Immunity - Antibodies and vaccination to practice offline. It includes additional chapter-level practice questions.