Human Physiology
Each subtopic includes About section, revision page link, 10 preview questions, and practice CTAs.
Digestion and Absorption
SubtopicDigestion and Absorption under Human Physiology for Grade 11 IB.
Preview questions (no answers)
- 1.
What is the purpose of having a very long small intestine in humans?
A.To store food for several days
B.To provide maximum time and surface area for absorption
C.To produce more hydrochloric acid
D.To prevent the growth of bacteria
- 2.
Which of the following best describes the process of ingestion?
A.Breaking down food using enzymes
B.Taking food into the mouth
C.Absorbing nutrients into the blood
D.Removing waste from the body
- 3.
Why can humans NOT digest cellulose?
A.The stomach acid is too weak to break it down
B.Human enzymes like amylase cannot break -1,4 linkages
C.Cellulose is too small to be targeted by enzymes
D.It is only found in animal tissues
- 4.
What is the name of the muscular ring that controls the exit of food from the stomach into the small intestine?
A.Cardiac sphincter
B.Pyloric sphincter
C.Anal sphincter
D.Epiglottis
- 5.
Why does the rate of starch digestion decrease if the temperature is raised to ?
A.The starch molecules become more stable.
B.The amylase enzymes denature.
C.The activation energy of the reaction increases.
D.Water evaporates from the digestive juices.
- 6.
What is the effect of the longitudinal muscles contracting during peristalsis?
A.The lumen of the gut narrows.
B.The gut becomes shorter and wider.
C.The food is pushed backward toward the mouth.
D.The circular muscles are inhibited from contracting.
- 7.
Which part of the digestive system has the lowest (most acidic) pH?
A.Mouth
B.Stomach
C.Duodenum
D.Ileum
- 8.
Which of the following is a characteristic feature of the villi that facilitates efficient absorption?
A.Thick muscular walls to pump nutrients
B.A single layer of epithelial cells providing a short diffusion path
C.A lack of blood vessels to prevent nutrient dilution
D.A highly acidic surface to further break down proteins
- 9.
Why does the rate of absorption decrease significantly if the microvilli are damaged (e.g., in celiac disease)?
A.The total surface area available for the insertion of transport proteins is reduced
B.The circular muscles can no longer perform peristalsis
C.The pancreas stops producing amylase
D.Bile can no longer enter the duodenum
- 10.
Which of the following processes occurs during the 'luminal' phase of starch digestion?
A.Hydrolysis of maltose into glucose by maltase
B.Hydrolysis of amylose into maltose by amylase
C.Absorption of glucose via the SGLT-1 transporter
D.Transport of glucose into the hepatic portal vein
Download the worksheet for Human Physiology - Digestion and Absorption to practice offline. It includes additional chapter-level practice questions.
The Blood System
SubtopicThe Blood System under Human Physiology for Grade 11 IB.
Preview questions (no answers)
- 1.
In which part of the body are red blood cells, white blood cells, and platelets primarily produced?
A.The heart
B.The liver
C.The bone marrow
D.The spleen
- 2.
Which of the following is a distinct characteristic of human red blood cells that helps maximize space for hemoglobin?
A.They have a very large nucleus
B.They lack a nucleus at maturity
C.They are spherical in shape
D.They have many mitochondria
- 3.
How are hormones such as insulin or adrenaline transported to their target organs?
A.Through specialized hormone ducts
B.By attachment to red blood cells
C.Dissolved in the blood plasma
D.Through the nervous system
- 4.
Where are the semilunar valves specifically located within the heart system?
A.Between the atria and the ventricles
B.At the openings of the vena cava
C.At the base of the aorta and pulmonary artery
D.Inside the pulmonary veins
- 5.
What occurs when the semi-lunar valves close?
A.The first heart sound 'lub' is heard
B.The second heart sound 'dub' is heard
C.The ventricles begin to contract
D.The atria begin to contract
- 6.
What is the primary function of leucocytes in the blood?
A.Transporting nutrients
B.Clotting of blood
C.Defending the body against infection
D.Maintaining osmotic pressure
- 7.
Which of the following is true about the pulmonary circulation?
A.It carries blood from the heart to the rest of the body
B.It operates at a higher pressure than systemic circulation
C.It involves the right side of the heart
D.It delivers oxygenated blood to the tissues
- 8.
How do the coronary arteries differ from most other systemic arteries in terms of when they receive the most blood flow?
A.They receive most of their blood during ventricular systole.
B.They receive most of their blood during ventricular diastole.
C.They receive a constant flow regardless of the cardiac cycle.
D.They only receive blood when the heart rate exceeds .
- 9.
Which of the following best explains why the pressure in the aorta never falls to zero, even when the heart is not contracting?
A.The aortic valve remains slightly open to allow continuous flow.
B.The atria contract during ventricular diastole to keep the aorta full.
C.The elastic walls of the aorta recoil and maintain pressure on the blood.
D.The skeletal muscle pump in the legs pushes blood back up to the aorta.
- 10.
A thrombus (clot) that forms in a coronary artery is particularly dangerous because it can lead to:
A.A stroke in the brain.
B.A myocardial infarction (heart attack).
C.A pulmonary embolism in the lungs.
D.A sudden rise in systemic blood pressure.
Download the worksheet for Human Physiology - The Blood System to practice offline. It includes additional chapter-level practice questions.
Defense Against Infectious Disease
SubtopicDefense Against Infectious Disease under Human Physiology for Grade 11 IB.
Preview questions (no answers)
- 1.
Which of the following is an example of an infectious disease?
A.Type 1 Diabetes
B.Scurvy
C.Tuberculosis
D.Color blindness
- 2.
What happens to the fibrinogen during the final stage of blood clotting?
A.It is broken down into amino acids
B.It is converted from a soluble form into an insoluble fibrous form
C.It is released from platelets into the air
D.It is used to synthesize new white blood cells
- 3.
Which of these contributes to the development of antibiotic-resistant bacteria?
A.Finishing the entire prescribed course of antibiotics
B.Using antibiotics for viral infections where they have no effect
C.The use of vaccinations against bacterial diseases
D.The presence of lysosomes in human phagocytes
- 4.
What is the result of the variable regions on an antibody being unique?
A.They can bind to any protein in the body
B.They allow the antibody to bind to one specific antigen
C.They allow the antibody to act as an enzyme for digestion
D.They make the antibody resistant to heat
- 5.
Which of the following is a characteristic of a secondary immune response compared to a primary response?
A.It involves phagocytes instead of lymphocytes
B.It produces a higher concentration of antibodies in a shorter time
C.It only occurs in the presence of antibiotics
D.It is slower because the body must create new antigens
- 6.
Smallpox was the first infectious disease to be eradicated worldwide. What was the primary reason for this success?
A.Smallpox viruses are extremely sensitive to penicillin
B.The virus only infects humans, and a global vaccination program was implemented
C.The virus mutated into a harmless form after many years
D.Improved sanitation led to the elimination of the smallpox vector
- 7.
Which enzyme is used by HIV to integrate its genetic material into the host cell's DNA?
A.DNA Polymerase
B.Reverse Transcriptase
C.Thrombin
D.Lysozyme
- 8.
What is the function of the 'constant region' of an antibody?
A.It determines the antigen specificity of the antibody
B.It binds to the epitope of the pathogen
C.It determines the class of the antibody (e.g., IgG vs IgE) and its secondary functions
D.It is the part of the antibody that undergoes somatic hypermutation
- 9.
Which of the following best describes the evolution of antibiotic resistance in bacteria?
A.Individual bacteria learn to tolerate the antibiotic and pass this knowledge to offspring
B.The antibiotic causes mutations in the bacteria that make them resistant
C.Random mutations provide a survival advantage in the presence of the antibiotic, leading to differential reproduction
D.Bacteria produce more offspring in the presence of antibiotics to ensure some survive
- 10.
What determines the ABO blood group of an individual?
A.The type of antibodies present on the surface of their white blood cells
B.The specific glycoprotein antigens present on the surface of their erythrocytes
C.The concentration of clotting factors in their plasma
D.The number of lysosomes in their macrophages
Download the worksheet for Human Physiology - Defense Against Infectious Disease to practice offline. It includes additional chapter-level practice questions.
Preview questions (no answers)
- 1.
Which of these are branches of the bronchi?
A.Trachea
B.Alveoli
C.Bronchioles
D.Capillaries
- 2.
Which of the following describes an 'antagonistic' muscle pair?
A.Two muscles that work together to perform the same movement
B.Two muscles that move in opposite directions to each other
C.A muscle and a bone working together
D.A muscle that never relaxes
- 3.
What happens to the pressure of air in the lungs when the ribcage is pulled upwards and outwards?
A.Pressure increases
B.Pressure decreases
C.Pressure remains unchanged
D.Pressure reaches equilibrium with the blood
- 4.
How does the oxygen level in the pulmonary vein compare to the pulmonary artery?
A.Oxygen is higher in the pulmonary vein
B.Oxygen is lower in the pulmonary vein
C.Oxygen levels are identical
D.The pulmonary vein does not contain oxygen
- 5.
In the context of the IB curriculum, which of the following is a direct consequence of a high concentration of in the blood?
A.The blood becomes more alkaline
B.The breathing rate increases to expel the gas
C.The diaphragm stays contracted for longer periods
D.The hemoglobin binds more tightly to oxygen
- 6.
Which of the following best describes the function of Type I pneumocytes?
A.They undergo mitosis rapidly to replace damaged lung tissue
B.They are specialized for gas exchange due to their large surface area and thinness
C.They secrete surfactant to keep the lungs moist
D.They contract to help push air out of the alveoli
- 7.
What role does the network of elastic fibers in the alveolar walls play?
A.They allow the alveoli to expand during inhalation and recoil during exhalation
B.They act as filters to trap dust particles that escaped the mucus
C.They provide the energy needed for the diffusion of gases
D.They connect the alveoli directly to the bronchioles
- 8.
Which of the following describes the correct condition for air to be exhaled from the lungs?
A.Atmospheric pressure must be lower than the pressure inside the thoracic cavity.
B.Atmospheric pressure must be higher than the pressure inside the thoracic cavity.
C.The diaphragm must be in a contracted, flattened state.
D.The volume of the thoracic cavity must increase.
- 9.
Which part of the brain is responsible for the unconscious control of the rhythm of ventilation?
A.The Cerebellum
B.The Corpus Callosum
C.The Medulla Oblongata
D.The Hypothalamus
- 10.
Which of the following is a direct consequence of the Bohr Effect during exercise?
A.Hemoglobin picks up more oxygen in the lungs.
B.Hemoglobin releases more oxygen to the tissues where levels are high.
C.The blood becomes more alkaline, improving oxygen transport.
D.The rate of ventilation decreases to conserve .
Download the worksheet for Human Physiology - Gas Exchange to practice offline. It includes additional chapter-level practice questions.
Neurons and Synapses
SubtopicNeurons and Synapses under Human Physiology for Grade 11 IB.
Preview questions (no answers)
- 1.
Which of these occurs first when an action potential reaches the synaptic knob?
A.Neurotransmitter breakdown
B.Opening of voltage-gated calcium channels
C.Binding of neurotransmitters to receptors
D.Opening of sodium channels on the post-synaptic membrane
- 2.
If multiple presynaptic neurons release neurotransmitters at the same time, what is this process called?
A.Saltation
B.Summation
C.Propagation
D.Depolarization
- 3.
What is the primary function of a relay neuron?
A.To detect changes in the environment
B.To carry signals from the CNS to muscles
C.To connect sensory and motor neurons within the CNS
D.To produce myelin for the peripheral nerves
- 4.
Why do neonicotinoids cause paralysis and death in insects but are less toxic to humans?
A.Humans do not have acetylcholine
B.Insects have more myelin than humans
C.Neonicotinoids bind much more strongly to insect receptors than human receptors
D.Humans do not have synapses
- 5.
Which describes the 'threshold' in the context of nerve impulses?
A.The minimum time between two action potentials
B.The maximum voltage a neuron can reach
C.The membrane potential at which an action potential is triggered
D.The total amount of neurotransmitter in a vesicle
- 6.
What occurs when acetylcholine binds to its receptor on the post-synaptic membrane?
A.Ligand-gated sodium channels open
B.Voltage-gated potassium channels close
C.The membrane becomes hyperpolarized
D.The pre-synaptic neuron is inhibited
- 7.
Which ion's movement is responsible for the rapid change from to ?
A.moving out
B.moving in
C.moving in
D.moving out
- 8.
A neuron is exposed to a toxin that keeps voltage-gated channels open longer than usual. What would be the effect on the oscilloscope trace?
A.The depolarization phase would be steeper.
B.The peak of the action potential would be higher.
C.The hyperpolarization phase would be deeper and longer.
D.The resting potential would become mV.
- 9.
What is the primary role of the phospholipid bilayer of the axon membrane in maintaining the resting potential?
A.It actively transports ions into the cell.
B.It acts as an insulator that prevents the free diffusion of ions.
C.It provides the energy (ATP) needed for ion movement.
D.It contains the receptors for acetylcholine.
- 10.
If the concentration outside a neuron was reduced, how would this affect the action potential?
A.The resting potential would become more negative.
B.The peak of the action potential would be lower (less positive).
C.Repolarization would occur more quickly.
D.The hyperpolarization phase would be eliminated.
Download the worksheet for Human Physiology - Neurons and Synapses to practice offline. It includes additional chapter-level practice questions.
Hormones, Homeostasis, and Reproduction
SubtopicHormones, Homeostasis, and Reproduction under Human Physiology for Grade 11 IB.
Preview questions (no answers)
- 1.
What is the function of the urethra in the male reproductive system?
A.It produces sperm
B.It transports both urine and semen out of the body
C.It stores sperm for maturation
D.It secretes testosterone into the blood
- 2.
Which of the following correctly pairs a hormone with its primary source?
A.Thyroxin - Pancreas
B.Glucagon - Thyroid gland
C.Insulin - Pancreas
D.Melatonin - Adipose tissue
- 3.
Which hormone is produced by the pineal gland?
A.Thyroxin
B.Leptin
C.Melatonin
D.Insulin
- 4.
What is the 'set point' in a homeostatic system?
A.The maximum possible value of a variable
B.The value at which a variable is normally maintained
C.The minimum possible value of a variable
D.The point where a hormone is no longer produced
- 5.
During IVF, what is checked in the embryos before they are implanted into the uterus?
A.Their ability to produce estrogen
B.Their health and viability (and sometimes genetic defects)
C.The presence of the gene in all cases
D.The amount of yolk they contain
- 6.
What is the source of the hormone that inhibits appetite?
A.The brain
B.The stomach
C.The fat stores of the body
D.The small intestine
- 7.
In the menstrual cycle, what is the role of the follicle?
A.To produce progesterone after ovulation.
B.To nourish the developing egg cell and secrete estrogen.
C.To travel down the fallopian tube to the uterus.
D.To provide the site for fertilization.
- 8.
If a person's body temperature is 38°C, which of the following is most likely occurring?
A.Arterioles near the skin surface are constricting.
B.The hypothalamus is sending signals to increase the metabolic rate.
C.Sweat glands are being stimulated to release moisture for evaporative cooling.
D.The person is shivering to generate more internal heat.
- 9.
Which condition results from the autoimmune destruction of -cells?
A.Type II Diabetes
B.Type I Diabetes
C.Hypothyroidism
D.Leptin Resistance
- 10.
What is the direct consequence of the LH surge in the ovary?
A.The completion of Meiosis II in the oocyte.
B.The rupture of the Graafian follicle and release of the secondary oocyte.
C.The immediate start of menstruation.
D.The transformation of the corpus luteum into a follicle.
Download the worksheet for Human Physiology - Hormones, Homeostasis, and Reproduction to practice offline. It includes additional chapter-level practice questions.
Hormones, homeostasis and reproduction
SubtopicHormones, homeostasis and reproduction under Human Physiology for Grade 11 IB.
Preview questions (no answers)
- 1.
In the male fetus, which hormone is secreted by the embryonic testes to promote the development of male internal reproductive organs?
A.Estrogen
B.Testosterone
C.FSH
D.LH
- 2.
What is the consequence of the body's cells becoming resistant to insulin?
A.Type I Diabetes
B.Type II Diabetes
C.Hyperthyroidism
D.Reduced leptin production
- 3.
When thyroxin levels are low, how does the body respond to maintain homeostasis?
A.By decreasing the basal metabolic rate
B.By increasing the production of thyroxin by the thyroid gland
C.By secreting more insulin
D.By increasing the rate of sweating
- 4.
Which hormone is responsible for the contraction of the uterus during childbirth through a positive feedback loop?
A.Progesterone
B.Oxytocin
C.Estrogen
D.Prolactin
- 5.
The flowchart below illustrates the structural changes that occur in an ovary during a typical 28-day menstrual cycle. What process is represented by 'X' and which pituitary hormone is primarily responsible for triggering this event?
A.Menstruation, triggered by a drop in progesterone
B.Ovulation, triggered by a surge in luteinizing hormone (LH)
C.Ovulation, triggered by a surge in follicle-stimulating hormone (FSH)
D.Follicle maturation, triggered by a rise in estrogen
- 6.
What is the immediate effect of a high blood glucose concentration on the beta cells of the pancreas?
A.They are inhibited from releasing any hormones
B.They secrete insulin into the bloodstream
C.They secrete glucagon into the bloodstream
D.They convert glucose into glycogen within the cell
- 7.
Which gland is both endocrine (secreting hormones into blood) and exocrine (secreting enzymes into ducts)?
A.Thyroid
B.Pancreas
C.Pineal
D.Adrenal
- 8.
Which hormone is most responsible for the thickening of the endometrium and the development of its blood supply during the post-ovulatory phase?
A.LH
B.FSH
C.Progesterone
D.Oxytocin
- 9.
How does the body's response to high blood glucose differ between a person with Type I diabetes and a person with Type II diabetes?
A.In Type I, insulin is not produced; in Type II, insulin is produced but the target cells are resistant.
B.In Type I, the liver ignores insulin; in Type II, the pancreas is destroyed by the immune system.
C.In Type I, glucose is converted to fat too quickly; in Type II, glucose is excreted by the lungs.
D.In Type I, the alpha cells are overactive; in Type II, the beta cells are overactive.
- 10.
What is the molecular basis of the 'set point' in temperature regulation in the hypothalamus?
A.The melting point of the lipid bilayer in hypothalamic neurons.
B.A specific firing rate of warm-sensitive and cold-sensitive neurons.
C.The concentration of glucose required to keep the hypothalamus functioning.
D.The rate at which thyroxin is degraded in the blood.
Download the worksheet for Human Physiology - Hormones, homeostasis and reproduction to practice offline. It includes additional chapter-level practice questions.
Muscle and motility (HL)
SubtopicMuscle and motility (HL) under Human Physiology for Grade 11 IB.
Preview questions (no answers)
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- Muscle and motility (HL): practice question 1 for Human Physiology?
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- Muscle and motility (HL): practice question 10 for Human Physiology?
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Download the worksheet for Human Physiology - Muscle and motility (HL) to practice offline. It includes additional chapter-level practice questions.
Chemical signalling (HL)
SubtopicChemical signalling (HL) under Human Physiology for Grade 11 IB.
Preview questions (no answers)
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- Chemical signalling (HL): practice question 1 for Human Physiology?
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- Chemical signalling (HL): practice question 9 for Human Physiology?
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- Chemical signalling (HL): practice question 10 for Human Physiology?
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Download the worksheet for Human Physiology - Chemical signalling (HL) to practice offline. It includes additional chapter-level practice questions.