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Cell Biology - Membrane Transport

Grade 11IBBiology

Review the key concepts, formulae, and examples before starting your quiz.

🔑Concepts

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The plasma membrane follows the Fluid Mosaic Model, consisting of a phospholipid bilayer where phospholipids are amphipathic, containing a hydrophilic phosphate head and two hydrophobic fatty acid tails.

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Simple Diffusion is the passive movement of small, non-polar molecules like O2O_2 and CO2CO_2 from a region of high concentration to low concentration until equilibrium is reached.

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Facilitated Diffusion involves the movement of polar molecules or ions (e.g., C6H12O6C_6H_{12}O_6, Cl−Cl^-, or Na+Na^+) across the membrane through specific channel or carrier proteins without the use of ATPATP.

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Osmosis is the net movement of H2OH_2O molecules across a partially permeable membrane from a region of lower solute concentration (hypotonic) to a region of higher solute concentration (hypertonic).

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Active Transport requires energy in the form of ATPATP to move substances against a concentration gradientconcentration \ gradient using protein pumps, such as the Sodium-Potassium pump (Na+/K+Na^+/K^+ pump).

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The Sodium-Potassium pump specifically moves 3 Na+3 \ Na^+ ions out of the cell and 2 K+2 \ K^+ ions into the cell to maintain resting potential in neurons.

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Vesicular transport involves the fluidity of the membrane to allow for endocytosisendocytosis (internalization of substances) and exocytosisexocytosis (secretion of substances), both of which are active processes.

📐Formulae

Rate of Diffusion∝Surface Area×Concentration GradientThickness of MembraneRate \ of \ Diffusion \propto \frac{Surface \ Area \times Concentration \ Gradient}{Thickness \ of \ Membrane}

%ΔMass=Mfinal−MinitialMinitial×100\% \Delta Mass = \frac{M_{final} - M_{initial}}{M_{initial}} \times 100

Ψ=Ψs+Ψp\Psi = \Psi_s + \Psi_p

💡Examples

Problem 1:

A tissue sample with an initial mass of 5.0 g5.0 \ g is placed in a solution. After 30 minutes, the final mass is 5.4 g5.4 \ g. Calculate the percentage change in mass and determine if the solution was hypotonic or hypertonic.

Solution:

Using the formula: %ΔMass=5.4 g−5.0 g5.0 g×100=+8.0%\% \Delta Mass = \frac{5.4 \ g - 5.0 \ g}{5.0 \ g} \times 100 = +8.0\%.

Explanation:

Because the percentage change is positive, the tissue gained mass. This indicates that H2OH_2O moved into the cells via osmosis, meaning the external solution had a lower solute concentration than the cytoplasm. Therefore, the solution was hypotonic.

Problem 2:

Describe the ratio of ions moved by the Na+/K+Na^+/K^+ pump and the energy requirement.

Solution:

3 Na+3 \ Na^+ ions are pumped out of the cell for every 2 K+2 \ K^+ ions pumped into the cell, consuming 11 molecule of ATPATP per cycle.

Explanation:

This is an example of primary active transport. The hydrolysis of ATPATP to ADP+PiADP + P_i provides the energy required to change the conformational shape of the integral protein pump.

Membrane Transport Grade 11 Notes & Examples | IB Biology