Review the key concepts, formulae, and examples before starting your quiz.
🔑Concepts
Modes of Excretion: Organisms are classified as Ammonotelic (excreting ), Ureotelic (excreting Urea ), or Uricotelic (excreting Uric acid ) based on their nitrogenous waste.
Human Excretory System: Consists of a pair of kidneys, a pair of ureters, a urinary bladder, and a urethra. Kidneys are situated between the levels of the and vertebrae.
Nephron Structure: The functional unit of the kidney, consisting of the Glomerulus and the Renal Tubule (Bowman's capsule, Proximal Convoluted Tubule (PCT), Henle's loop, and Distal Convoluted Tubule (DCT)).
Glomerular Filtration Rate (GFR): The amount of filtrate formed by the kidneys per minute. In a healthy individual, it is approximately , which totals .
Urine Formation: Involves three main processes: Ultrafiltration (occurring in the Malpighian corpuscle), Reabsorption (mostly in the PCT where of electrolytes and are reclaimed), and Secretion (, , and into the filtrate).
Counter Current Mechanism: Operates between the Henle's loop and Vasa recta to maintain an osmolarity gradient in the medullary interstitium, increasing from in the cortex to in the inner medulla.
Regulation of Kidney Function: Controlled by the Antidiuretic Hormone (ADH), the Renin-Angiotensin-Aldosterone System (RAAS), and the Atrial Natriuretic Factor (ANF).
Micturition: The process of release of urine, regulated by the central nervous system through the micturition reflex.
📐Formulae
(Net Filtration Pressure)
💡Examples
Problem 1:
Calculate the Net Filtration Pressure () if the Glomerular Hydrostatic Pressure () is , the Blood Colloidal Osmotic Pressure () is , and the Capsular Hydrostatic Pressure () is .
Solution:
Explanation:
The Net Filtration Pressure is the total pressure that promotes filtration. It is calculated by subtracting the opposing pressures ( and ) from the promoting pressure ().
Problem 2:
Explain why only of urine is excreted daily even though of filtrate is formed.
Solution:
Explanation:
Nearly of the filtrate is reabsorbed by the renal tubules through active and passive transport mechanisms to prevent the loss of essential water and solutes like , Glucose, and Amino Acids.