Review the key concepts, formulae, and examples before starting your quiz.
🔑Concepts
Cell Theory: Proposed by Matthias Schleiden and Theodore Schwann, later modified by Rudolf Virchow with the phrase '', meaning all cells arise from pre-existing cells.
Prokaryotic Cells: Generally smaller ( to ) and lack a membrane-bound nucleus and organelles. Genetic material is naked (Genophore/Nucleoid).
Cell Envelope (Prokaryotes): Consists of a three-layered structure: the outermost Glycocalyx (slime layer or capsule), the Cell Wall, and the Plasma Membrane.
Mesosomes: Specialized membranous structures in prokaryotes formed by the extension of the plasma membrane into the cell, helping in cell wall formation and DNA replication.
Eukaryotic Cells: Characterized by an organized nucleus with a nuclear envelope and membrane-bound organelles like Mitochondria, Chloroplasts, and Golgi bodies.
Fluid Mosaic Model: Proposed by Singer and Nicolson (), stating that the plasma membrane is a 'mosaic' of proteins embedded in a fluid lipid bilayer composed of phosphoglycerides.
Ribosomes: Sites of protein synthesis. Prokaryotes have (composed of and subunits) while Eukaryotes have (composed of and subunits) in the cytoplasm.
Endomembrane System: A coordinated group of organelles including the Endoplasmic Reticulum (ER), Golgi complex, Lysosomes, and Vacuoles.
Mitochondria: The 'powerhouse' of the cell, possessing a double membrane. The inner membrane forms infoldings called cristae to increase surface area for production.
Cytoskeleton: An elaborate network of filamentous proteinaceous structures (microtubules, microfilaments) that provide mechanical support and motility.
Cilia and Flagella: Hair-like outgrowths of the cell membrane. Eukaryotic flagella show a '' arrangement of microtubules covered by a plasma membrane.
📐Formulae
(Where is the Svedberg unit/Sedimentation coefficient, is sedimentation velocity, and is acceleration)
(For a cubical cell of side , showing why smaller cells are more efficient)
💡Examples
Problem 1:
Calculate the sedimentation coefficient of a ribosome if it is described as . What do the subunits and signify in terms of mathematics?
Solution:
The '' stands for Svedberg unit ( seconds). The subunits and do not add up mathematically to because is a measure of density and shape (sedimentation rate) rather than additive mass.
Explanation:
Sedimentation units are determined by how fast a particle settles in a centrifuge; the shape of the combined complex results in a different sedimentation rate than the sum of its individual parts.
Problem 2:
A cell has a diameter of . If a molecule travels at a rate of , how long does it take to cross the cell?
Solution:
Explanation:
This demonstrates the importance of the small size of cells in ensuring rapid diffusion and transport of materials like and nutrients.